ED guide · Medicines and ED

Does Adderall Cause ED? What the Labels Say

Short answer

Yes—ED is a reported sexual side effect: the Adderall (amphetamine mixed salts) label lists “Impotence, changes in libido, frequent or prolonged erections.” If this started while taking Adderall, ask your prescriber about it without stopping or changing the medicine yourself (Adderall (amphetamine mixed salts) label).

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On this page Jump to a section
  1. Key facts
  2. Can Adderall cause erectile dysfunction?
  3. Adderall and ED: what the labels say
  4. Can you take Viagra with Adderall?
  5. What each path includes
  6. What to bring to your prescriber or ED visit
  7. Safety checks before ED medication
  8. If ED is the problem you want treated now
  9. Mendoxa plans and prices
  10. FAQ
  11. How we wrote this
  12. Sources and references

Key facts at a glance

Label wording
“Impotence, changes in libido, frequent or prolonged erections.”Adderall (amphetamine) label · DailyMed
How often
Impotence and decreased libido: within a group of reactions reported by 2 to 4% of adults in one Adderall XR studyAdderall XR (amphetamine) label · DailyMed
Heart and blood pressure
Mean rise about 2 to 4 mm Hg and 3 to 6 bpm; some patients have larger increasesAdderall (amphetamine) label · DailyMed
With sildenafil
No amphetamine interaction listed; nitrates are contraindicatedViagra (sildenafil) label · DailyMed
Compounded status
The Mendoxa compounded tablet is not FDA-approvedFDA compounding Q&A

Can Adderall cause erectile dysfunction?

The labels support a possible link, not a diagnosis of your symptoms. The Adderall XR (amphetamine mixed salts) label explains that voluntary postapproval reports cannot reliably establish how often a reaction occurs or whether the drug caused it.

Describe the problem you want help with: firmness, sexual desire, or erections that last longer than expected—the Adderall (amphetamine mixed salts) label lists these as distinct reported changes. Read performance anxiety and ED if anxiety is also part of your question; NIDDK lists anxiety, stress and depression among possible contributors.

Taking a blood pressure medicine too? Our lisinopril and ED guide covers that separate medication question.

Adderall and ED: what the labels say

Use this evidence table to separate what is reported from what is known about frequency. Sources checked Oct 22, 2026.

Adderall and ED: what the labels say · accessed Oct 22, 2026
Label entryExact wording or findingWhat it does not tell you
Adderall tablet: adverse reactions, Endocrine“Impotence, changes in libido, frequent or prolonged erections.” (Adderall (amphetamine mixed salts) label)No frequency is given for these entries
Adderall XR: adult study (191 treated; 64 placebo)“libido decreased” and “impotence” were among reactions “reported by 2 to 4% of adult patients receiving ADDERALL XR with a higher incidence than patients receiving placebo” (Adderall XR (amphetamine mixed salts) label)This is a grouped range from one study, not a separate ED rate
Adderall XR: postapproval reportsReported reactions include “Impotence, changes in libido, frequent or prolonged erections”; such reports make it “not always possible to reliably estimate their frequency or establish a causal relationship” (Adderall XR (amphetamine mixed salts) label)Whether Adderall caused your own symptoms
Adderall: blood pressure and heart rateMean increase about 2 to 4 mm Hg in blood pressure and about 3 to 6 bpm in heart rate; “Some patients may have larger increases” (Adderall (amphetamine mixed salts) label)The labels do not link this to erections
Adderall: heart diseaseAvoid use with known structural cardiac abnormalities, cardiomyopathy, serious arrhythmia, coronary artery disease or other serious cardiac disease (Adderall (amphetamine mixed salts) label)Your own cardiac status: that needs a clinician
Viagra, Cialis and APOKYN interaction listsNo amphetamine interaction listed in the Viagra (sildenafil) label, Cialis (tadalafil) label or APOKYN (apomorphine) labelNo listed interaction is not the same as a safety clearance; a provider reviews every medicine

Sources: Adderall (amphetamine mixed salts) tablet label, Teva, 5/2024; Adderall XR (amphetamine mixed salts) label, Takeda, 4/2026; Viagra (sildenafil) label; Cialis (tadalafil) label; APOKYN (apomorphine) label. Accessed Oct 22, 2026.

Can you take Viagra with Adderall?

No direct amphetamine interaction is listed in the Viagra (sildenafil) label or Cialis (tadalafil) label. That does not establish that taking them with Adderall is safe for you; these labels require consideration of cardiovascular health.

The Adderall (amphetamine mixed salts) label warns about increased blood pressure and heart rate and advises avoiding use in serious cardiac disease. The Viagra (sildenafil) label says ED treatment should generally not be used when sexual activity is inadvisable because of cardiovascular status; the Cialis (tadalafil) label also sets cardiovascular restrictions.

Tell your provider about every medicine before adding ED treatment. Sildenafil and tadalafil are contraindicated with organic nitrates and riociguat (Viagra (sildenafil) label; Cialis (tadalafil) label). Read ED medication and nitrates and ED and blood pressure to prepare your questions.

What each path includes

Choose the next conversation by the problem you want addressed. Bring a medication timeline to your ADHD prescriber; use an ED visit to ask about treatment suitability. You can raise both questions without deciding the cause yourself.

Adderall and ED care: what each path includes · accessed Oct 22, 2026
PathQuestion it addressesWhat it includesBoundary
ADHD prescriber reviewIs Adderall part of the problem?Timing of symptoms, dose and possible changes; “Your healthcare provider may change the dose if needed” (Adderall (amphetamine mixed salts) label)Discuss changes with the clinician prescribing it
ED assessmentWhat else could be causing ED?Medical, sexual and mental health history, a physical exam and tests, including the medicines you take (NIDDK)A medicine side effect is one cause among several
Standalone ED prescriptionIs an ED medicine suitable with Adderall?Sildenafil or tadalafil if appropriate, after a cardiovascular review (Viagra (sildenafil) label; Cialis (tadalafil) label)The approved ingredient labels do not establish suitability for you
Mendoxa 3-in-1 visitDoes the compounded tablet fit?Online intake that asks about your current medicines; Independent licensed providers review it; Prescription requiredCompounded drugs are not FDA-approved

Sources: Adderall (amphetamine mixed salts) label; NIDDK diagnosis; Viagra (sildenafil) label; Cialis (tadalafil) label; FDA compounding Q&A; Mendoxa ED care information. Accessed Oct 22, 2026.

Compare ED medication options and the broader erectile dysfunction guide before the visit.

Could Mendoxa ED care fit you?

Online ED visit · Prescription required · Independent licensed providers · Not available in California

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What to bring to your prescriber or ED visit

Keep taking ADHD medicine as prescribed while arranging a review. The Adderall (amphetamine mixed salts) label describes withdrawal after abrupt discontinuation or dose reduction following prolonged use; discuss any change with your prescriber.

Prepare a short note for the visit: your medicine name and prescribed dose, start date, any changes, when erection or desire changes began, and all other medicines, vitamins and supplements. The Adderall (amphetamine mixed salts) label asks patients to share their medicine list; NIDDK’s ED assessment guidance also includes medicine history.

Useful questions: “Could my medicine be contributing?” “What else should be assessed?” and “Would an ED prescription fit my health history?” See ED medication options and how ED is assessed and treated.

Safety checks before ED medication

Do not add another ED medicine to an existing treatment on your own: the Viagra (sildenafil) label and Cialis (tadalafil) label say combinations with other PDE5 inhibitors or ED therapies have not been studied and advise against such use.

If ED is the problem you want treated now

Start the online visit to find out whether Mendoxa ED care is appropriate for you. Share your symptoms, health history and current medicines, including Adderall; the Adderall (amphetamine mixed salts) label asks patients to tell their clinician about all medicines. Independent licensed providers assess suitability. Prescription required.

The tablet combines sildenafil, tadalafil and apomorphine; it is not FDA-approved. Ingredient references are the Viagra (sildenafil) label, Cialis (tadalafil) label and APOKYN (apomorphine) label; APOKYN is an injectable Parkinson’s treatment, and its label is not approval of this ED combination.

Learn about the compounded combination ED tablet before choosing. The online visit is the next step in assessing suitability; the costs below apply if prescribed.

Mendoxa ED plans and prices

The Mendoxa ED tablet is a compounded rapid-dissolve tablet with sildenafil (the active ingredient in Viagra), tadalafil (the active ingredient in Cialis) and apomorphine (APOKYN label). It dissolves under the tongue. A licensed clinician decides if it fits you and selects the strength. Compounded medicines are not FDA-approved.

Mendoxa ED plans from the intake, accessed Oct 22, 2026
Tablets per month1-month totalPer tablet (1 month)3-month totalPer tablet (3 months)
6 tablets / month$129$21.50$329$18.28
10 tablets / month$149$14.90$379$12.63
20 tablets / month$179$8.95$449$7.48

The 3-month total covers three months at the monthly tablet quantity shown.

If prescribed · Cancel anytime · Available in 49 states (not California). Prices from the Mendoxa intake at try.mendoxa.co/f/ed on Oct 22, 2026. The intake always shows the current price.

FAQ

Does Adderall-related ED go away?

The labels do not say how long it lasts or whether it reverses. The Adderall XR (amphetamine mixed salts) label notes that postapproval reports cannot reliably establish frequency or causation. Ask your ADHD prescriber about timing or dose rather than stopping, because the Adderall (amphetamine mixed salts) label describes withdrawal after abrupt discontinuation.

Can you take Viagra with Adderall?

The Viagra (sildenafil) label and Cialis (tadalafil) label list no direct interaction with amphetamine, but both ask prescribers to consider cardiovascular status. The Adderall (amphetamine mixed salts) label reports blood pressure and heart rate increases, so a provider should review your heart health and every medicine first.

Does Adderall make you last longer in bed?

The Adderall (amphetamine mixed salts) label lists frequent or prolonged erections as reported reactions; it does not establish a benefit for delaying ejaculation. An erection lasting more than 4 hours needs immediate medical care under the Viagra (sildenafil) label and Cialis (tadalafil) label warnings.

Does Adderall lower sex drive?

The Adderall XR (amphetamine mixed salts) label lists decreased libido among reactions reported in an adult study, while the Adderall (amphetamine mixed salts) label uses the broader wording “changes in libido.” Tell your prescriber whether the problem is reduced desire, erection firmness, or both.

Is it Adderall or anxiety causing my ED?

The labels cannot tell you that. The Adderall (amphetamine mixed salts) label lists impotence as a reported reaction, while NIDDK lists anxiety, depression and stress among other causes of ED; an ED assessment looks at both.

Can I get ED treatment online if I take Adderall?

You can start an online ED visit; the Mendoxa intake asks about current medicines and Independent licensed providers decide suitability. Prescription required. The compounded tablet is not FDA-approved, its ingredients are referenced in the Viagra (sildenafil) label and Cialis (tadalafil) label.

Ready to see if the Mendoxa ED tablet fits you?

From $129/month if prescribed · Cancel anytime · Available in 49 states (not California)

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How we wrote this

Written by the Mendoxa editorial team · Sources: DailyMed/FDA. Medical facts on this page come from the FDA-approved labels on DailyMed and Drugs@FDA; each drug name links to its label. We checked the Adderall (amphetamine mixed salts) label, Adderall XR (amphetamine mixed salts) label, Viagra (sildenafil) label and Cialis (tadalafil) label on Oct 22, 2026, distinguishing trial results from postapproval reports. The absence of an amphetamine interaction in these ED labels is a label-text finding, not evidence that a combination is safe for everyone. Ingredient labels describe their approved products; they do not establish safety or effectiveness of Mendoxa’s compounded combination.

Updated Oct 22, 2026. This page is general information, not medical advice. A licensed clinician decides what fits you.

References

  1. DailyMed: VIAGRA (sildenafil citrate) tablet, film coated, label revised 12/2017. Accessed Oct 22, 2026.
  2. DailyMed: CIALIS (tadalafil) tablet, film coated, label revised 3/2026. Accessed Oct 22, 2026.
  3. DailyMed: APOKYN (apomorphine hydrochloride) injection, label revised 6/2022. Accessed Oct 22, 2026.
  4. FDA (Drugs@FDA): VIAGRA (sildenafil) prescribing information, NDA 020895. Accessed Oct 22, 2026.
  5. FDA (Drugs@FDA): CIALIS (tadalafil) prescribing information, NDA 021368. Accessed Oct 22, 2026.
  6. FDA: Compounding and the FDA, questions and answers. Accessed Oct 22, 2026.
  7. DailyMed: ADDERALL (amphetamine mixed salts) tablet, Teva, label revised 5/2024. Accessed Oct 22, 2026.
  8. DailyMed: ADDERALL XR (amphetamine mixed salts) extended-release capsules, Takeda, label revised 4/2026. Accessed Oct 22, 2026.
  9. NIDDK: symptoms and causes of ED. Accessed Oct 22, 2026.
  10. NIDDK: diagnosis of ED. Accessed Oct 22, 2026.
  11. Mendoxa ED care (product, format, max 1 dose per 24 hours). Accessed Oct 22, 2026.
  12. Mendoxa ED intake: plan prices (term_options). Accessed Oct 22, 2026.

About Mendoxa

Mendoxa (mendoxa.co) is a US telehealth brand. Independent licensed providers (licensed clinicians in the LocumTele network) review each online visit, and prescriptions are filled by Rush Pharmacy, a licensed US pharmacy. Available in 49 states (not California).

  • Prescription required. A licensed clinician reviews every visit and can say no. A prescription is not automatic.
  • A compounded medicine is not an FDA-approved finished product (FDA compounding Q&A).
  • Plans: 1 month or 3 months, from $129. If prescribed · Cancel anytime · Available in 49 states (not California).

Explore Mendoxa ED care

Compounded medication prescribed only if a licensed U.S. clinician decides it is appropriate. Not FDA-approved as a finished product. Not available in California. This site is not for emergencies. Call 911 if you need urgent care.